Molybdenum disulfide-based materials with enzyme-like characteristics for biological applications

Nanozyme, a kind of nanomaterials with enzymatic activity, has been developing vigorously over the past years owing to its advantages such as low-cost, easy storage, ease of use in harsh environments and so on, compared with natural enzymes. At present, as a typical two-dimensional nanomaterial, molybdenum disulfide (MoS₂) and their hybrids with unexpected enzyme-like activities have caused wide attention. In this review, we mainly investigated the enzyme-like activities of MoS₂ based nanomaterials, including peroxidase-like activity, catalase-like activity and superoxide dismutase-like activity. Furthermore, we systematically introduce recent research progress of MoS₂ based nanomaterials in the fields of biological applications such as radiation protection, cancer therapy, antibacterial, and wound healing. Finally, the current challenges and perspectives of MoS₂ based nanomaterials in the future are also discussed and proposed. We expect this review may be significant to understand the properties of MoS₂ based nanomaterials and the development of two-dimensional nanomaterials with enzyme mimicking activities.