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The Retromer Complex: From Genesis to Revelations.

Matthew N J Seaman1

  • 1University of Cambridge, Cambridge Institute for Medical Research, The Keith Peters Building, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK.

Trends in Biochemical Sciences
|February 2, 2021
PubMed
Summary

The retromer complex sorts endosomal proteins, crucial for cell function. Its dysfunction is linked to neurodegenerative diseases like Alzheimer's and Parkinson's, making it a therapeutic target.

Keywords:
endosomemembraneneurodegenerative diseaseretromersorting nexintherapeutic targettubules

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