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Nitroso-aldicarb induces sister-chromatid exchanges in human lymphocytes in vitro
M G González Cid1, D Loria, E Matos
1Instituto de Oncología Angel H. Roffo, Departamento de Investigaciones, Buenos Aires, Argentina.
Mutation Research
|April 1, 1988
Abstract:
Nitroso-aldicarb was tested for its ability to induce sister-chromatid exchanges (SCE) and cell-cycle delay in human peripheral blood lymphocytes in vitro. This derivative of aldicarb induced a dose-dependent increase in SCE values per cell. In addition, a slight decrease in the successive mitotic progression of cells in culture was observed.