Related Experiment Video

Updated: Nov 19, 2025

Pairwise Growth Competition Assay for Determining the Replication Fitness of Human Immunodeficiency Viruses

Pairwise Growth Competition Assay for Determining the Replication Fitness of Human Immunodeficiency Viruses

Published on: May 4, 2015

Urine Tenofovir Levels Measured Using a Novel Immunoassay Predict Human Immunodeficiency Virus Protection

Randy M Stalter^1,2, Jared M Baeten^1,2,3, Deborah Donnell^1,4

¹Department of Global Health, University of Washington, Seattle, Washington, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America

|February 2, 2021

Abstract:

New tools are needed to support pre-exposure prophylaxis (PrEP) adherence for human immunodeficiency virus (HIV) prevention, including those that enable real-time feedback. In a large, completed PrEP trial, adequate urine tenofovir levels measured using a novel immunoassay predicted HIV protection and showed good sensitivity and specificity for detectable plasma tenofovir.

Keywords:

PrEP ELISA HIV prevention immunoassay urine

More Related Videos

Prediction of HIV-1 Coreceptor Usage Tropism by Sequence Analysis using a Genotypic Approach

Prediction of HIV-1 Coreceptor Usage Tropism by Sequence Analysis using a Genotypic Approach

Published on: December 1, 2011

Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays

Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays

Published on: September 26, 2011

Related Concept Videos

Articles linked to this work by shared authors, journal, and citation graph.

Community Perspectives and Behavior Change Strategies for Integrated Long-Acting Reversible Contraception and Long-Acting Injectable Preexposure Prophylaxis Roll Out for Adolescent Girls and Young Women in Uganda (COMPASS): Protocol for a Mixed Methods Implementation Science Study.

JMIR research protocols·2026

Associations between self-reported PrEP use and short and long-term pharmacologic metrics of PrEP adherence among Kenyan women.

Journal of acquired immune deficiency syndromes (1999)·2026

Same-day initiation of tenofovir alafenamide-based pre-exposure prophylaxis with drug-level feedback for transgender women in Uganda.

AIDS (London, England)·2026

Provider Preferences on Existing and Potential Future Biomedical HIV Prevention Products: A Qualitative Study in the United States, Thailand, and South Africa.

AIDS research and human retroviruses·2026

Sex differences in long-acting cabotegravir trough concentrations in the SEARCH study in Kenya and Uganda.

AIDS (London, England)·2026

Syphilis clustering among young pregnant women (18-35 years) in Kampala and Wakiso districts, Uganda.

Frontiers in reproductive health·2026

See all related articles