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Terbinafine-Induced Acute Generalized Exanthematous Pustulosis
Bernardo Correia1, Joana Costa1, Paula Egipto2
1Plastic and Reconstructive Surgery - Burn Unit, Centro Hospitalar Universitário de São João, Porto, Portugal.
Summary
Severe cutaneous adverse drug reactions are rare but serious. This case highlights terbinafine-induced acute generalized pustulosis, emphasizing prompt diagnosis and specialized care for better outcomes.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Severe cutaneous adverse drug reactions (SCARs) are uncommon but critical medical events.
- Prompt diagnosis and management are essential for patient prognosis.
Observation:
- A rare and severe case of terbinafine-induced acute generalized pustulosis is presented.
- The patient required direct admission to a Burn Unit for specialized care.
Findings:
- Diagnostic confirmation and histopathological analysis are crucial for SCARs.
- Systemic supportive care and wound management were key treatment components.
Implications:
- Accurate differential diagnosis of SCARs is fundamental for appropriate treatment strategies.
- Understanding drug-induced dermatoses like pustulosis is vital for clinical practice.
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