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Effects of serial administration of kainic acid on the developing brain
1Department of Neurology, Medical College of Georgia, Augusta.
Neuropharmacology
|February 1, 1988
Abstract:
The purpose of this study was to determine whether the repeated administration of kainic acid at 24-hr intervals results in pharmacological kindling. Rather than developing an increased intensity of seizures, this method of serial administration of kainic acid resulted in the development of tolerance to its effects.