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Published on: September 26, 2019
Prevalence of atopic diseases in children with papular urticaria
Mehmet Halil Celiksoy1, Abdullah Hakan Ozmen2, Erdem Topal3
1Department of Pediatric Allergy and Immunology, Gaziosmanpasa Education and Research Hospital, Istanbul, Turkey; drmhc@hotmail.com.
Insights
Papular urticaria in children is often linked to atopic diseases. This study found higher rates of conditions like atopic dermatitis and asthma in children with papular urticaria, suggesting a need for comprehensive assessment.
Area of Science:
- Pediatric Allergy and Immunology
- Dermatology
- Clinical Epidemiology
Background:
- Papular urticaria is a common hypersensitivity reaction in children, often triggered by insect bites.
- It presents as chronic, recurrent papular erythema, particularly in pediatric populations.
- The association between papular urticaria and underlying atopic diseases requires further investigation.
Purpose of the Study:
- To determine the prevalence of atopic diseases in children diagnosed with papular urticaria.
- To compare the incidence of atopic conditions in pediatric papular urticaria patients versus age-matched controls.
Main Methods:
- Retrospective review of medical records for 130 pediatric patients with papular urticaria.
- Patients were categorized into two age groups: under 5 years and over 5 years.
- Comparison of atopic disease prevalence with age-matched control groups without papular urticaria.
Main Results:
- Higher prevalences of atopic disease, recurrent wheezing, and atopic dermatitis were observed in papular urticaria patients under 5 compared to controls.
- Children over 5 with papular urticaria showed significantly higher rates of atopic disease, asthma, allergic rhinitis, and atopic dermatitis than controls.
- Statistical significance (p<0.007) was established for all observed differences between patient and control groups.
Conclusions:
- A significant proportion of children with papular urticaria also have atopic conditions.
- Pediatric patients diagnosed with papular urticaria should be evaluated for comorbid atopic diseases.
- This highlights the importance of a holistic approach to managing papular urticaria in children.
Background:
Papular urticaria is a hypersensitivity reaction characterized by chronic and recurrent papular erythema. It occurs as a result of the bites of mosquitoes, fleas, bed bugs, and other insects; and it is generally seen in children. This study examines the prevalence of atopic diseases in patients with papular urticaria.
Methods:
The medical records of 130 pediatric patients with the diagnosis of papular urticaria between August 2017 and August 2019, whose disease progression was followed in two tertiary care centers, were reviewed retrospectively. The patients were divided into two groups: under 5 and above 5 years old. The prevalence of the atopic disease in children with papular urticaria was compared with those in age-matched controls without papular urticaria.
Results:
The study included 130 patients who were diagnosed with papular urticaria (64 males, 66 females, median age: 60 months). The prevalences of atopic disease, recurrent wheezing, and atopic dermatitis were higher in the group under 5 years old with papular urticaria than in the same-age control group (p=0.001, 0.002, and 0.001, respectively). The prevalences of atopic disease, asthma, allergic rhinitis, and atopic dermatitis were higher in the group above 5 years old with papular urticaria than in the same-age control group (p=0.001, 0.001, 0.001, and 0.007, respectively).
Conclusions:
Many children with papular urticaria are atopic children. These patients should be assessed not only in terms of papular urticaria but also in terms of comorbid atopic diseases.
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