Inhaled corticosteroids may have a protective effect against coronavirus infection

Area of Science:

• Pulmonology
• Infectious Diseases
• Epidemiology

Background:

• Spain experienced a severe COVID-19 epidemic, with significant mortality.
• Vulnerable populations, including the elderly with pre-existing conditions, faced the highest risk.

Purpose of the Study:

• To compare respiratory symptoms in nursing home residents and patients with uncontrolled asthma.
• To assess the vulnerability of these groups to COVID-19.

Main Methods:

• A study involving 134 nursing home residents and 139 patients with uncontrolled asthma.
• Data collection included demographics, clinical data, outcomes, lab results, and radiological images.
• COVID-19 infection was confirmed via polymerase chain reaction (PCR).

Main Results:

• COVID-19 infection occurred in 9.3% of uncontrolled asthma patients, all using inhaled corticosteroids.
• Infection affected 60% of nursing home residents, with 28 (using inhaled corticosteroids) showing good prognosis.

Conclusions:

• Early treatment with inhaled corticosteroids may be beneficial for COVID-19 patients.
• Individuals with allergies may possess protective mechanisms against coronavirus.