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Updated: Nov 19, 2025

Functional Assessment of the Donor Heart During Ex Situ Perfusion: Insights from Pressure-Volume Loops and Surface Echocardiography
Published on: October 11, 2022
Extracorporeal circulation during on-pump cardiac surgery: An evaluation of the energy equivalent pressure index
Agnès Drochon1, Olivier Fouquet2, Christophe Baufreton2
1Arts et Metiers Institute of Technology, Bordeaux INP, INRAE, I2M Bordeaux, CNRS, University of Bordeaux, Talence, France.
Abstract:
The use of pulsatile perfusion instead of nonpulsatile perfusion during cardiopulmonary bypass continues to be a source of debate. The disagreements among the conclusions of the published studies may be due to different factors: differences in the type of patients included in the studies, differences in the protocol of the studies, and difficulty to quantify the pulsatility of the flow. In the present paper, we propose a quantitative evaluation of Shepard's energy equivalent pressure index, based on the harmonic decomposition of the physiological aortic pressure and flow rate signal. It is thus demonstrated that the surplus energy provided by pulsatile flow remains moderate (of order 10 mm Hg), but that it can be improved by changing the relative shapes of the pressure and flow waves.
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