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Visualizing the 'backbone' of focal adhesions

Samuel F H Barnett1, Pakorn Kanchanawong1,2

  • 1Mechanobiology Institute, National University of Singapore, Singapore 117411.

Emerging Topics in Life Sciences
|February 3, 2021
PubMed
Summary

Focal adhesions (FAs) are complex cell structures. Talin acts as a backbone, linking integrin and actin, and its engineered length changes the FA nanostructure, revealing its role in cell organization.

Keywords:
cell adhesioncytoskeletonsuper-resolution microscopy

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