Association of skin and other lesions with cervical dysplasia

Association is reported in a series of 805 patients between cervical dysplasia and the occurrence of lesions in other organs, in particular the skin. The occurrence of associated lesions in these patients was markedly in excess of that in case-matched controls. It was not related to the increased frequency of gynaecological investigation in patients with cervical dysplasia. Pigmented naevi were the most common associated lesions, occurring before and after the diagnosis of cervical dysplasia. Three cases of malignant melanoma were seen in the test group. Gynaecological lesions were also common. The findings are discussed in the light of recent work on viral synergism in genital neoplasia.