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COVID-2019 Associated with Acquired Monocular Blindness.
Ling Liu1, Danrui Cai1, Xin Huang1
1Eye Center, Wuhan University Renmin Hospital, Wuhan University, Wuhan, China.
Current Eye Research
|February 3, 2021
Summary
This case study reports a rare instance of acquired monocular blindness in an older female with Coronavirus Disease 2019 (COVID-19). The findings suggest a potential link between SARS-CoV-2 infection and severe vision loss, including acute viral retinitis.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Virology
Background:
- Coronavirus Disease 2019 (COVID-19) is a global pandemic with diverse clinical manifestations.
- Ocular complications associated with COVID-19 are increasingly reported, but severe vision loss is rare.
Observation:
- An older female patient with COVID-19 presented with acquired monocular blindness.
- Ocular examinations revealed severe retinal arterial ischemia and elevated intraocular pressure.
- COVID-19 nucleic acid was detected in nasopharyngeal swabs and tear samples.
Findings:
- The patient exhibited significant vision loss in one eye, with characteristic signs of retinal arterial ischemia.
- Flash visual evoked potential testing indicated reduced wave amplitude in the affected eye.
- SARS-CoV-2 IgM antibodies were detected in blood, and viral RNA was confirmed in ocular secretions.
Implications:
- This case highlights acute viral retinitis as a potential complication of COVID-19, leading to severe vision loss.
- Clinicians should consider SARS-CoV-2 infection in patients presenting with sudden vision loss or funduscopic abnormalities.
- Further research is needed to elucidate the mechanisms of ocular involvement in COVID-19.
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