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Primary gastric Ewing sarcoma/primitive neuroectodermal tumor.

Yu Ye1,2, Xiaoming Qiu1,2, Jixin Mei1,2

  • 1Department of Radiology, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Edong Health Care Group, Huangshi, Hubei, China.

The Journal of International Medical Research
|February 3, 2021
PubMed
Summary
This summary is machine-generated.

This case report details an extremely rare instance of primary gastric Ewing sarcoma (ES), a malignant small round cell tumor. The 55-year-old patient underwent surgery, highlighting the diagnostic and therapeutic challenges of this unusual presentation.

Keywords:
Ewing sarcomacluster of differentiation 99gastricprimaryprimitive neuroectodermal tumorstomach

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Area of Science:

  • Oncology
  • Pathology
  • Gastroenterology

Background:

  • Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) is a rare, highly malignant small round cell tumor.
  • While typically found in bone or soft tissues, extraosseous ES/PNET is exceptionally uncommon in the stomach.

Observation:

  • A 55-year-old woman presented with symptoms including fatigue, fever, and black stool.
  • Imaging revealed a large ulcerative lesion in the stomach, measuring approximately 5.5 x 5.0 cm.
  • Histopathology confirmed a 7.5 cm mass as ES, with CD99 positivity.

Findings:

  • The patient was diagnosed with primary gastric Ewing sarcoma after whole-body CT showed no other masses.
  • The patient underwent radical distal gastrectomy with Roux-en-Y gastrojejunostomy.
  • The patient declined chemoradiotherapy post-surgery.

Implications:

  • This case underscores the importance of considering rare diagnoses like primary gastric ES in patients with unexplained gastrointestinal lesions.
  • Early and accurate diagnosis through imaging and histopathology is crucial for appropriate management.
  • Further research into the optimal treatment strategies for primary gastric ES is warranted due to its rarity.