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Updated: Nov 19, 2025

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
COVID-19 and emergencies in patients with diabetes: two case reports
Rajib Kumar Dey1, Abdullah Isneen Hilmy2, Hisham Ahmed Imad3,4
1Department of Internal Medicine, Indira Gandhi Memorial Hospital, Male', Maldives. dr_rajibdey@yahoo.co.uk.
Insights
COVID-19 patients with diabetes face higher risks of severe complications like diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS). Prompt monitoring and aggressive management of these diabetic emergencies are crucial for better outcomes.
Area of Science:
- Endocrinology
- Infectious Diseases
- Nephrology
Background:
- The Maldives reported its first COVID-19 case in March 2020, with over 9400 cases and 33 deaths.
- COVID-19 patients with diabetes exhibit poorer prognoses and higher mortality rates.
- Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are potentially lethal complications that can be precipitated by COVID-19 in poorly controlled diabetic patients.
Observation:
- Two cases of diabetic emergencies in COVID-19 patients are presented.
- Case 1: A 53-year-old male with moderate COVID-19 presented with DKA and acute kidney injury.
- Case 2: A 72-year-old male with mild COVID-19 developed HHS and acute kidney injury.
Findings:
- Both patients were managed conservatively in the ICU with intravenous fluids and insulin.
- The study highlights a scarcity of reported cases of diabetic emergencies during the pandemic, despite frequent reports of uncontrolled diabetes.
Implications:
- Clinicians must closely monitor diabetic patients with COVID-19 to prevent emergencies like DKA and HHS.
- Aggressive management of these diabetic emergencies is essential for favorable patient outcomes.
- This underscores the critical interplay between diabetes management and COVID-19 care.
Background:
Maldives reported its first Coronavirus disease 2019 (COVID-19) case on March 7th, 2020. Since then more than 9400 positive cases and 33 deaths have been reported. Recently studies have shown that COVID-19 patients with diabetes had a poor prognosis and a higher mortality rate when compared to the non-diabetic patients. Poorly controlled diabetic patients had a higher incidence of complications like diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) which might have been precipitated by COVID-19. DKA and HHS are potentially lethal but preventable conditions. During this pandemic, although cases of uncontrolled diabetes are frequently reported, there is scarcity in reporting of cases with diabetic emergencies.
Case Presentation:
Case 1 was a 53-year old Asian male, admitted on Day 10th of illness with DKA with acute kidney injury, and Moderate COVID-19. Case 2 was a 72-year old Asian male, admitted with mild COVID-19 who developed HHS with acute kidney injury on day 9 of illness. Both patients were managed conservatively in intensive care unit, with intravenous fluids and insulin.
Conclusion:
Clinicians should focus on close monitoring of diabetic patients with COVID-19, to prevent diabetic emergencies like DKA and HHS. It is important to aggressively manage these conditions for a favorable outcome.
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