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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Updated: Nov 19, 2025

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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Aniridic glaucoma: An update.

F J Muñoz-Negrete1, M A Teus2, J García-Feijoó3

  • 1Servicio de Oftalmología, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, España; Universidad de Alcalá, Alcalá de Henares, España; OFTARED.

Archivos De La Sociedad Espanola De Oftalmologia
|February 3, 2021
PubMed
Summary
This summary is machine-generated.

Aniridic glaucoma (AG) affects over 50% of patients with aniridia. Management involves medical therapies and surgical interventions, with specific approaches depending on the glaucoma

Keywords:
AniridiaAniridic glaucomaCongenital glaucomaGlaucomaGlaucoma InfantilGlaucoma anirídicoGlaucoma congénitoInfantile glaucoma

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Area of Science:

  • Ophthalmology
  • Genetics
  • Glaucoma Research

Background:

  • Aniridia is a congenital disorder with dominant inheritance.
  • Over 50% of aniridia patients develop aniridic glaucoma (AG).
  • AG diagnosis is challenging due to associated ocular conditions like keratopathy and nystagmus.

Purpose of the Study:

  • To review the challenges and management strategies for aniridic glaucoma.
  • To discuss current treatment options for open-angle and closed-angle AG.
  • To highlight the difficulties in intraocular pressure measurement in aniridia patients.

Main Methods:

  • Literature review of aniridic glaucoma diagnosis and treatment.
  • Analysis of medical and surgical management approaches.
  • Discussion of challenges in AG patient follow-up.

Main Results:

  • Aniridic glaucoma presents diagnostic and management complexities.
  • Medical treatment for AG is similar to general glaucoma, favoring preservative-free options.
  • Surgical choices for AG vary, with angle surgery or drainage devices for open-angle, and drainage devices or trabeculectomy for closed-angle forms.

Conclusions:

  • Effective management of aniridic glaucoma requires tailored strategies.
  • Accurate intraocular pressure measurement is often hindered by corneal thickness.
  • Further research may clarify optimal surgical interventions for different AG subtypes.