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A case of lymphomatoid papulosis type E in a young adult: An uncommon entity
Meghana Rajashekara Swamy1, Samara Pollock1, Lynne J Goldberg1,2
1Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts, USA.
Abstract:
Lymphomatoid papulosis (LyP) type E is a rare variant of the primary cutaneous CD30+ lymphoproliferative disorders, characterized clinically by large necrotic eschar-like lesions and histopathologically by angiodestructive and angioinvasive infiltrates of CD30+ lymphocytes. As in other forms of lymphomatoid papulosis, type E lesions may undergo spontaneous regression after weeks, with frequent recurrences. We report a 21-year old male with an angiodestructive infiltrate of CD30+ lymphocytes manifesting as a papular eruption rather than ulceration, and suggest that this clinical phenotype might be related to the presence of CD4+ lymphocytes in the inflammatory cell infiltrate.
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