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Extremely and very preterm-born children <1500 g show different weight development in childhood compared to their

Inga Geisler1, Tanja Katrin Rausch1,2, Wolfgang Göpel1

  • 1Department of Paediatrics, University of Luebeck, Luebeck, Germany.

Acta Paediatrica (Oslo, Norway : 1992)
|February 3, 2021
PubMed

Insights

Reference growth charts were developed for extremely preterm (EPT) and very preterm (VPT) children. While length percentiles were comparable, these children exhibited lower BMI and head circumference compared to national references.

Area of Science:

  • Pediatrics
  • Neonatology
  • Growth and Development

Background:

  • Extremely preterm (EPT) and very preterm (VPT) infants (<1500g) often experience growth deviations.
  • Establishing accurate growth references is crucial for monitoring their development.

Purpose of the Study:

  • To create reference growth charts for body mass index (BMI), weight, length, and head circumference in EPT and VPT children.
  • To compare the growth patterns of EPT and VPT children with national reference curves.

Main Methods:

  • Analysis of EPT and VPT children from the German Neonatal Network (2009-2013).
  • Data split into training and validation sets; validation dataset included 385 EPT and 491 VPT children from birth to 6 years.
  • Growth charts calculated using validated data.

Main Results:

  • Length percentiles for EPT and VPT children were comparable to German references.
  • An attenuated BMI peak and lower BMI were observed in all analyzed EPT and VPT children.
  • Head circumference was lower in EPT and VPT boys and girls from 2 to 6 years of age.

Conclusions:

  • Modern EPT cohorts do not show the height deficits seen in earlier decades.
  • EPT and VPT children display distinct BMI growth patterns compared to national references.
  • The developed growth charts serve as a tool for assessing EPT and VPT child growth.
Abstract

Keywords:
body mass indexhead circumferenceinfantlengthprematureweight

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