Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

AI-assisted Radiomic Model for Cervical Cancer Recurrence Prediction: A Multicenter Retrospective Study with Experimental Validation.

Radiology. Imaging cancer·2026
Same author

Effect of histology on the efficacy of first-line immune checkpoint inhibitors in advanced non-small cell lung cancer: a systematic review and network meta-analysis.

Frontiers in immunology·2026
Same author

Pancreatic islet α cell function and proliferation require the arginine transporter SLC7A2.

The Journal of clinical investigation·2026
Same author

Author Correction: PCM1 orchestrates centrosomal and flagellar protein transport to promote sperm maturation.

Communications biology·2026
Same author

The regulatory roles of non-coding RNAs in aerobic glycolysis and therapeutic potential in pancreatic ductal adenocarcinoma.

Annals of medicine·2026
Same author

Application of Ultrasonication as an Emerging Non-Thermal Physical Technology in Meat Product Processing: A Review.

Foods (Basel, Switzerland)·2026

Related Experiment Video

Updated: Nov 18, 2025

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
05:05

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration

Published on: November 23, 2019

8.3K

Fully Automatic Sliding Motion Compensated and Simultaneous 4D-CBCT via Bilateral Filtering.

Jun Dang1, Tao You2, Wenzheng Sun3

  • 1Department of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Frontiers in Oncology
|February 4, 2021
PubMed
Summary

This study introduces a new method for automatic sliding motion compensation in 4D-CBCT imaging using bilateral filtering. The technique significantly improves motion estimation and image reconstruction accuracy for lung SBRT treatments.

Keywords:
4D-CBCTbilateral filteringdeformable vector fieldssimultaneous reconstructionsliding motion

More Related Videos

Automated Midline Shift and Intracranial Pressure Estimation based on Brain CT Images
14:08

Automated Midline Shift and Intracranial Pressure Estimation based on Brain CT Images

Published on: April 13, 2013

43.1K
Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

864

Related Experiment Videos

Last Updated: Nov 18, 2025

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
05:05

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration

Published on: November 23, 2019

8.3K
Automated Midline Shift and Intracranial Pressure Estimation based on Brain CT Images
14:08

Automated Midline Shift and Intracranial Pressure Estimation based on Brain CT Images

Published on: April 13, 2013

43.1K
Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

864

Area of Science:

  • Medical Imaging
  • Image Reconstruction
  • Computational Anatomy

Background:

  • 4D-CBCT is crucial for image-guided radiotherapy.
  • Accurate motion compensation is essential for effective treatment, especially for lung SBRT.
  • Current methods for sliding motion compensation in 4D-CBCT require manual intervention or lack precision.

Purpose of the Study:

  • To develop a fully automatic sliding motion compensated 4D-CBCT reconstruction method.
  • To incorporate bilateral filtering into Deformable Vector Field (DVF) based 4D-CBCT.
  • To enhance the accuracy of motion estimation and image quality in 4D-CBCT.

Main Methods:

  • A motion compensated simultaneous algebraic reconstruction technique (mSART) was used to generate a reference phase.
  • Deformable Vector Fields (DVFs) were iteratively updated by matching projections.
  • A novel bilateral filtering kernel was integrated into the DVF smoothing constraint to automatically estimate sliding motion.

Main Results:

  • The bilateral filtering approach significantly reduced motion trajectory errors (RMSE/MaxE) on a phantom compared to original methods.
  • Improved 4D-Dice coefficients were observed in patient data, indicating better organ delineation.
  • Enhanced visualization of anatomical structures like rib position and heart edges was achieved.

Conclusions:

  • A novel, fully automatic bilateral filtering-based 4D-CBCT scheme for sliding motion compensation was successfully developed.
  • The method demonstrated improved motion estimation and image reconstruction capabilities in phantom and pilot patient studies.
  • This technique holds promise as an advanced image guidance tool for lung SBRT.