Related Experiment Video

Updated: Nov 18, 2025

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring
06:29

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring

Published on: May 2, 2025

467

Long-term results of concomitant atrioventricular valve intervention and the Fontan operation

Yang Yang1, Zicong Feng1, Kai Ma1

  • 1Pediatric Cardiac Surgery Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|February 4, 2021
PubMed

Insights

Optimal timing for atrioventricular valve (AVV) repair in Fontan circulation is debated. Concomitant AVV repair with Fontan operation shows favorable long-term outcomes, though AVV function may decline over time.

Area of Science:

  • Cardiology
  • Pediatric Cardiac Surgery
  • Congenital Heart Disease

Background:

  • The optimal timing for atrioventricular valve (AVV) repair in patients with Fontan circulation is not well-established.
  • Few studies have investigated the long-term outcomes of AVV repair performed concurrently with the Fontan operation.

Purpose of the Study:

  • To evaluate the long-term outcomes of concomitant atrioventricular valve (AVV) repair during the Fontan operation.
  • To compare outcomes between patients who underwent concomitant AVV repair and those who did not.

Main Methods:

  • A retrospective study of 89 patients with moderate or severe AVV regurgitation before Fontan operation from 2006-2018.
  • Patients were divided into two groups: 37 without concomitant AVV repair (Group 1) and 52 with concomitant AVV repair (Group 2).

Main Results:

  • Freedom from long-term death, reduced cardiac function, and protein-losing enteropathy were similar between groups.
  • Atrioventricular valve (AVV) function was poorer after repair compared to mitral valve function (HR 3.83).
  • AVV valve failure occurred less frequently in Group 1 (no repair) than Group 2 (concomitant repair) (HR 0.44), with AVV function worsening over time in both groups.

Conclusions:

  • Concomitant atrioventricular valve (AVV) repair during the Fontan operation demonstrates favorable long-term results.
  • While AVV function may deteriorate post-repair, the procedure appears safe and effective in the long term for selected patients.
Abstract

Keywords:
Atrioventricular valve regurgitationFontan failureFontan operationValve failure

More Related Videos

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.4K
A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position11:20

A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position

Published on: April 1, 2022

3.3K

Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
173
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
144
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
110
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
124
Heart Valves01:16

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
9.7K