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Updated: Nov 18, 2025

Efficient Sporulation of Saccharomyces cerevisiae in a 96 Multiwell Format
Published on: September 17, 2016
Regulation of pro-σK activation: a key checkpoint in Bacillus subtilis sporulation
Gaohui Sun1, Moua Yang2, Longguang Jiang1,3
1College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350016, China.
Abstract:
The Gram-positive bacterium Bacillus subtilis initiates the sporulation process under conditions of nutrient limitation. Here, we review related work in this field, focusing on the protein processing of the pro-σK activation. The purpose of this review is to illustrate the mechanism of pro-σK activation and provide structural insights into the regulation of spore production. Sporulation is not only important in basic science but also provides mechanistic insight for bacterial control in applications in, e.g., food industry.
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