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Updated: Nov 18, 2025

Visualizing Single Molecular Complexes In Vivo Using Advanced Fluorescence Microscopy
Published on: September 8, 2009
The molecular vista: current perspectives on molecules and life in the twentieth century
Mathias Grote1, Lisa Onaga2, Angela N H Creager3
1Institut für Geschichtswissenschaften, Humboldt-Universität zu Berlin, Friedrichstraße 191-193, 10099, Berlin, Germany. mathias.grote@hu-berlin.de.
Abstract:
This essay considers how scholarly approaches to the development of molecular biology have too often narrowed the historical aperture to genes, overlooking the ways in which other objects and processes contributed to the molecularization of life. From structural and dynamic studies of biomolecules to cellular membranes and organelles to metabolism and nutrition, new work by historians, philosophers, and STS scholars of the life sciences has revitalized older issues, such as the relationship of life to matter, or of physicochemical inquiries to biology. This scholarship points to a novel molecular vista that opens up a pluralist view of molecularizations in the twentieth century and considers their relevance to current science.
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