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Spinal Hemangioblastomas and Neuropathic Pain
Mustafa Umut Etli1, Caner Sarıkaya1, Mehmet Resid Onen2
1Department of Neurosurgery, Health Sciences University, Ümraniye Training and Research Hospital, Istanbul, Turkey.
World Neurosurgery
|February 4, 2021
Summary
Neuropathic pain (NP) is common in spinal hemangioblastomas (SHs). Dorsal tumor location and rostral syrinx significantly increase postoperative NP risk in patients with these rare tumors.
Area of Science:
- Neurosurgery
- Neurology
- Oncology
Background:
- Spinal hemangioblastomas (SHs) are rare, benign tumors.
- Common symptoms include pain, hypoesthesia, and neuropathic pain (NP).
- NP in SHs has not been previously studied.
Purpose of the Study:
- To investigate the incidence and causes of NP in patients with SHs.
- To identify factors contributing to NP development, both pre- and postoperatively.
Main Methods:
- Retrospective analysis of 13 patients with SHs.
- Evaluation of NP presence/absence in relation to tumor and syrinx characteristics.
- Correlation of NP with tumor level, location, size, and syrinx size/location.
Main Results:
- Postoperative NP occurred in 6 of 13 patients.
- All patients with postoperative NP had dorsal tumors.
- Rostral syrinx location was more common in patients with NP.
Conclusions:
- NP is present pre- and postoperatively in SH patients.
- Dorsal tumor proximity to the dorsal root entry zone and rostral syrinx are key factors for postoperative NP.
- Postoperative NP may result from these factors combined with iatrogenic injury.
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