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Decline and Recurrence of Stroke Consultations during the COVID-19 Pandemic Lockdown Parallels Population Activity
Felix Schlachetzki1, Sibylle Wilfling2, Nikolai Dominik Hubert3
1Department of Neurology, TEMPiS Telemedical Stroke Center, Bezirksklinikum Regensburg, University of Regensburg, Regensburg, Germany, felix.schlachetzki@klinik.uni-regensburg.de.
Insights
COVID-19 lockdown significantly reduced ischemic stroke (IS) admissions. While numbers increased after easing restrictions, they did not reach pre-lockdown levels, correlating with public transport mobility. Further research on pandemic responses and stroke is needed.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- The COVID-19 pandemic lockdown (CPL) led to a global decrease in emergency admissions.
- Ischemic stroke (IS) consultations and treatments were analyzed before, during, and after CPL.
Purpose of the Study:
- To analyze the impact of CPL on ischemic stroke (IS) and related consultations.
- To correlate IS events with mobile phone mobility data during different CPL phases.
Main Methods:
- Data from 12 hospitals on IS, IV rtPA, and EVT were analyzed from Feb 1 to June 15, 2017-2020.
- Mobile phone mobility data was correlated with IS event occurrences.
Main Results:
- A significant reduction in IS, IV rtPA, and EVT cases was observed during CPL compared to pre-lockdown (p<0.048).
- Post-lockdown, consultations and IS cases increased but remained below pre-lockdown levels.
- Consultation numbers closely paralleled public transportation mobility data.
Conclusions:
- Reduced emergency admissions during CPL may be partly due to patients avoiding care and decreased exposure to common viral triggers.
- The decline in stroke consultations correlated with reduced public transport use.
- Further studies are needed to compare national responses to the pandemic and stroke incidence.
Background:
The COVID-19 pandemic lockdown (CPL) lead to a significant decrease in emergency admissions worldwide. We performed a timely analysis of ischemic stroke (IS) and related consultations using the telestroke TEMPiS "working diagnosis" database prior (PL), within (WL), and after easing (EL) of CPL.
Methods:
Twelve hospitals were selected and data analyzed regarding IS (including intravenous thrombolysis [intravenous recombinant tissue plasminogen; IV rtPA] and endovascular thrombectomy [EVT]) and related events from February 1 to June 15 during 2017-2020. In addition, we aimed to correlate events to various mobile phone mobility data.
Results:
Following the significant reduction of IS, IV rtPA, and EVT cases during WL compared to PL in 2020 longitudinally (p values <0.048), we observed increasing numbers of consultations, IS, recommendations for EVT, and IV rtPA with the network in EL over WL not reaching PL levels yet. Absolute numbers of all consultations paralleled best to mobility data of public transportation over walking and driving mobility.
Conclusions:
While the decrease in emergency admissions including stroke during CPL can only be in part attributed by patients not seeking medical attention, stroke awareness in the pandemic, and direct COVID-19 triggered stroke remains of high importance. The number of consultations in TEMPiS during the lockdown parallels best with mobility of public transportation. As a consequence, exposure to common viruses, well-known triggers for acute cerebrovascular events and other diseases, are reduced and may add to the decline in stroke consultations. Further studies comparing national responses toward the course of the COVID-19 pandemic and stroke incidences are needed.
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