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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
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Transcatheter Mitral Valve Replacement: A Novel Anchor Technology.
Yazhou Liu1,2, Georg Lutter1,3, Philipp Knueppel1,3
1Department of Experimental Cardiac Surgery and Heart Valve Replacement, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, Germany.
The Thoracic and Cardiovascular Surgeon
|February 4, 2021
Summary
New anchoring technology for mitral valved stents was developed using 3D printing. This innovation improves stent fixation to the mitral annulus, preventing migration and leakage in high-pressure environments.
Area of Science:
- Biomedical Engineering
- Cardiovascular Devices
- Medical Device Technology
Background:
- Mitral valved stents are prone to migration and paravalvular leakage due to high left-ventricular pressure.
- Existing stent designs require improved anchoring mechanisms for enhanced stability.
Purpose of the Study:
- To develop and evaluate a novel anchoring technology for mitral valved stents.
- To improve the fixation of mitral nitinol stents to the mitral annulus.
Main Methods:
- Four anchoring units with curved surgical needles were designed using 3D software and fabricated with 3D printing technology.
- Mitral nitinol stents with integrated anchoring units were implanted on 10 porcine annuli.
- Mechanical tests were conducted to assess the fixation strength and stability of the anchored stents.
Main Results:
- The anchoring units demonstrated significant fixation strength, with average maximum force of 28.3 N and break force of 18.5 N.
- Puncture needles successfully engaged the mitral annulus in all specimens, with minimal myocardial penetration in one case.
- Anchoring units enhanced stent tightness without damaging adjacent cardiac structures.
Conclusions:
- 3D-printed anchoring units provide a viable solution for securely fixing mitral valved stents.
- This novel technology effectively addresses mitral valved stent migration and paravalvular leakage concerns.
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