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Updated: Nov 18, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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Chemogenetic approaches to identify metabolically important GPCR signaling pathways: Therapeutic implications

Jaroslawna Meister1, Lei Wang1, Sai P Pydi1

  • 1Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA.

Journal of Neurochemistry
|February 4, 2021
PubMed
Abstract

Keywords:
DREADD technologyG protein-coupled receptorsG proteinsmutant mouse modelsobesitytype 2 diabetes

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