Removal of Sulfadiazine by Polyamide Nanofiltration Membranes: Measurement, Modeling, and Mechanisms

In this study, a complete steric, electrostatic, and dielectric mass transfer model is applied to investigate the separation mechanism of typical antibiotic sulfadiazine by NF90, NF270, VNF-8040 and TMN20H-400 nanofiltration membranes. FTIR and XPS analysis clearly indicate that the membranes we used possess skin layers containing both amine and carboxylic acid groups that can be distributed in an inhomogeneous fashion, leading to a bipolar fixed charge distribution. We compare the theoretical and experimental rejection rate of the sulfadiazine as a function of the pressure difference across the nanopore for the four polyamide membranes of inhomogeneously charged nanopores. It is shown that the rejection rate of sulfadiazine obtained by the solute transport model has similar qualitative results with that of experiments and follows the sequence: RNF90>RVNF2-8040>RNF270>RTMN20H-400. The physical explanation can be attributed to the influence of the inhomogeneous charge distribution on the electric field that arises spontaneously so as to maintain the electroneutrality within the nanopore.