Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thymoma: a clinico-pathologic study based on newly developed morphologic criteria.

E A Rendina1, E O Pescarmona, F Venuta

  • 1Thoracic Surgery, University of Rome, La Sapienza, Italia.

Tumori
|February 29, 1988
PubMed
Summary

Cortical thymoma is linked to higher malignancy and invasiveness, while medullary thymoma shows less aggressive behavior. This study correlates thymoma histology with clinical outcomes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Letter: gluten challenge in the era of noncoeliac gluten sensitivity--a change in clinical practice? Author's reply.

Alimentary pharmacology & therapeutics·2016
Same author

Violence and unsafety in a major Italian hospital: experience and perceptions of health care workers.

La Medicina del lavoro·2015
Same author

Editorial: noncoeliac gluten sensitivity - the controversy rages on. Authors' reply.

Alimentary pharmacology & therapeutics·2015
Same author

Adiposity and risk of thyroid cancer: a systematic review and meta-analysis.

Obesity reviews : an official journal of the International Association for the Study of Obesity·2015
Same author

The risk for type B aortic dissection in Marfan syndrome.

The Journal of cardiovascular surgery·2015
Same author

Randomised clinical study: gluten challenge induces symptom recurrence in only a minority of patients who meet clinical criteria for non-coeliac gluten sensitivity.

Alimentary pharmacology & therapeutics·2015

Area of Science:

  • Oncology
  • Pathology
  • Clinical Medicine

Background:

  • Thymoma classification systems are crucial for understanding tumor behavior.
  • The Marino and Müller-Hermelink classification categorizes thymomas based on histological subtypes.
  • Correlating histological subtypes with clinical presentation is essential for patient management.

Purpose of the Study:

  • To investigate the relationship between thymoma histology and clinical behavior.
  • To determine if specific thymoma subtypes correlate with invasiveness and associated syndromes.

Main Methods:

  • A retrospective analysis of 28 thymoma cases.
  • Classification of thymomas using the Marino and Müller-Hermelink system.
  • Correlation of histological subtypes with clinical staging (Bergh) and associated conditions.

Related Experiment Videos

Main Results:

  • Cortical thymomas (39.2%) were consistently invasive (stages II-III).
  • Medullary thymomas (10.7%) were predominantly non-invasive (stage I) or minimally invasive (stage II).
  • Mixed thymomas exhibited intermediate invasiveness. Myasthenia gravis was most common with mixed common thymoma (6/9 cases).

Conclusions:

  • Thymoma histology significantly correlates with clinical behavior and invasiveness.
  • Cortical thymomas demonstrate a higher degree of malignancy.
  • Further research into specific subtype associations with paraneoplastic syndromes is warranted.