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Updated: Nov 18, 2025

Imaging Ca2+ Signals in Small Pulmonary Veins at Physiological Intraluminal Pressures
Published on: March 21, 2025
Advanced Imaging in Pulmonary Vascular Disease
Eileen M Harder1, Rebecca Vanderpool2, Farbod N Rahaghi1
1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, 15 Francis Street, Boston, MA 02115, USA.
Advanced imaging aids in screening, classifying, and monitoring pulmonary vascular disease (PVD). Novel techniques improve understanding of PVD pathophysiology and patient risk stratification.
Area of Science:
- Cardiology
- Radiology
- Pulmonology
Background:
- Pulmonary hypertension diagnosis is invasive.
- Imaging is crucial for pulmonary vascular disease (PVD) management.
- Advanced imaging enhances PVD understanding.
Purpose of the Study:
- To review current advanced imaging techniques for PVD.
- To discuss emerging imaging methods for PVD.
- To highlight imaging's role in PVD assessment.
Main Methods:
- Review of current literature on advanced imaging in PVD.
- Discussion of novel imaging techniques.
- Focus on visualization of lung, mediastinum, and heart.
Main Results:
- Advanced imaging improves PVD pathophysiology understanding.
- Noninvasive hemodynamic assessment is enhanced.
- Patient risk stratification is improved.
Conclusions:
- Imaging is vital for PVD screening, classification, and monitoring.
- Advanced and novel techniques offer significant benefits.
- Further research into imaging modalities is warranted.
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