Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patterns and Factors Associated With Cerebral Infarction on MRI in Tuberculous Meningitis: Secondary Analysis of the ACT-TBM Trial.

Stroke·2026
Same author

HMNR7 as a Neuromyopathy-A Novel VWA1 Variant With Minipolymyoclonus, Fasciculations, and Scapular Winging.

Muscle & nerve·2025
Same author

Neuro-ophthalmology of Infectious Diseases.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2025
Same author

Diagnosing tuberculous meningitis from cell-free DNA by multi-targeted real-time PCR: An experience from 170 cases.

Tuberculosis (Edinburgh, Scotland)·2025
Same author

Teaching NeuroImage: Multiple Symmetric Lipomatosis as a Manifestation of Mitochondrial Cytopathy.

Neurology·2025
Same author

Podophyllotoxin Revisited: Unveiling a Rare Cause of Sensory Ataxic Neuropathy.

Annals of Indian Academy of Neurology·2025

Related Experiment Video

Updated: Nov 18, 2025

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
26:48

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

Published on: July 4, 2007

18.5K

Subacute sclerosing panencephalitis and brain stem involvement: a rare combination.

Heena Kathuria1,1, Nandita Prabhat1, Ritu Shree1

  • 1Department of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

BMJ Case Reports
|February 5, 2021
PubMed
Summary

Subacute sclerosing panencephalitis (SSPE) is a rare, fatal measles virus infection of the brain. This case highlights unusual brainstem-dominant SSPE, emphasizing vigilance for atypical presentations.

Keywords:
brain stem / cerebelluminfection (neurology)

More Related Videos

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

2.6K
Author Spotlight: Unveiling the Pathway Linking Obesity to Autoimmune Inflammation in Multiple Sclerosis
08:17

Author Spotlight: Unveiling the Pathway Linking Obesity to Autoimmune Inflammation in Multiple Sclerosis

Published on: February 23, 2024

5.1K

Related Experiment Videos

Last Updated: Nov 18, 2025

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
26:48

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

Published on: July 4, 2007

18.5K
Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

2.6K
Author Spotlight: Unveiling the Pathway Linking Obesity to Autoimmune Inflammation in Multiple Sclerosis
08:17

Author Spotlight: Unveiling the Pathway Linking Obesity to Autoimmune Inflammation in Multiple Sclerosis

Published on: February 23, 2024

5.1K

Area of Science:

  • Neurology
  • Virology
  • Pediatric Neurology

Background:

  • Subacute sclerosing panencephalitis (SSPE) is a progressive, lethal neurological disease caused by persistent measles virus infection.
  • Typically affects children and adolescents, often involving parieto-occipital brain regions.
  • Atypical presentations occur in up to 10% of cases, with brainstem involvement being rare.

Purpose of the Study:

  • To report an unusual case of SSPE with extensive brainstem involvement.
  • To highlight the importance of considering SSPE in cases with atypical MRI findings, particularly brainstem hyperintensities.

Main Methods:

  • Case report of a 15-year-old male patient with SSPE.
  • Magnetic Resonance Imaging (MRI) of the brain to assess lesion distribution.

Main Results:

  • The patient presented with SSPE and extensive brainstem involvement on MRI.
  • Cortical structures showed no significant involvement, an atypical finding for SSPE.
  • This presentation is rarely described in the literature.

Conclusions:

  • Vigilance for brainstem and cerebellar involvement is crucial in diagnosing SSPE.
  • SSPE should not be overlooked in patients with brainstem hyperintensities on MRI, even without other typical brain region involvement.
  • Early diagnosis and consideration of atypical presentations can prevent misdiagnosis.