Related Experiment Video
Updated: Nov 18, 2025

Setup of Consumer Wearable Devices for Exposure and Health Monitoring in Population Studies
Published on: February 3, 2023
Risk of major cardiovascular events according to educational level before and after the initial COVID-19 public
Julie Andersen1, Katrine Strandberg-Larsen2, Thomas Gerds3,4
1Department of Cardiovascular Research, The Danish Heart Foundation, Copenhagen, Denmark juliea@hjerteforeningen.dk.
Insights
The COVID-19 lockdown reduced hospitalizations for major cardiovascular events (MCE), particularly in elderly, low-educated individuals. This highlights a potential for undertreatment, widening health disparities.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Decreased cardiovascular disease hospitalizations during COVID-19 raised concerns about undertreatment.
- Vulnerable populations may be disproportionately affected by changes in healthcare access.
Purpose of the Study:
- To investigate the impact of the initial COVID-19 public lockdown on the risk of major cardiovascular events (MCE) hospitalization.
- To analyze this impact across different educational attainment levels.
Main Methods:
- Danish residents were categorized by education level (low, medium, high) and age group.
- Age- and sex-standardized MCE hospitalization risks were compared between the 2020 lockdown period and the 2019 period.
- Differential effects of the lockdown on MCE incidence by educational level were assessed.
Main Results:
- MCE hospitalizations decreased from 2700 in 2019 to 2290 during the 2020 lockdown.
- The risk of MCE hospitalization significantly decreased for elderly (≥70 years) with low or medium education.
- No significant decrease in MCE hospitalization risk was observed for high-educated residents or younger age groups.
Conclusions:
- The COVID-19 lockdown correlated with reduced MCE incidence, especially in elderly, low-educated individuals.
- This trend raises concerns about potential undertreatment within this demographic.
- Urgent clinical awareness and intervention are needed to prevent widening educational disparities in cardiovascular outcomes.
Background:
During the COVID-19 pandemic, decreasing rates of hospitalisations for cardiovascular disease raised concerns for undertreatment, particularly for vulnerable groups. We investigated how the initial COVID-19 public lockdown, impacted the risk of being hospitalised with a major cardiovascular event (MCE: myocardial infarction/stroke/heart failure) according to educational level.
Methods:
We grouped all Danish residents according to educational attainment level (low, medium, high) and age (40-59, 60-69, ≥70 years). In each group, we calculated the age-standardised and sex standardised risk of MCE hospitalisation in the initial COVID-19 lockdown-period (13 March 2020-3 May 2020) and in the corresponding calendar period in 2019. We calculated age-standardised and sex-standardised risks to investigate whether the COVID-19 lockdown had a differential effect on MCE incidence according to educational level.
Results:
In the period in 2019, 2700 Danish residents were hospitalised with MCE, compared with only 2290 during the lockdown. During lockdown, the risk of hospitalisation for MCE decreased among residents aged ≥70 with low education (risk difference (RD) -46.2 (-73.2; -19.2) per 100,000) or medium education (RD -23.2 (-50.8; 4.3) per 100 000), but not among residents with high education (RD 5.1 (-32.3; 42.5), per 100 000). The risk of hospitalisation for MCE did not decrease significantly for the younger age groups.
Conclusions:
The COVID-19 lockdown is associated with a reduced incidence for MCE, especially among low educated, elderly residents. This raises concern for undertreatment that without clinical awareness and action may widen the educational gap in cardiovascular morbidity and mortality.
Related Concept Videos
Coronary Artery Disease IV: Preventive Measures
Relative Risk
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Factors affecting Blood pressure
Physiological Factors:

