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Does control affect growth in diabetes mellitus?
1Department of Paediatrics, Sheffield Children's Hospital, University of Sheffield, UK.
Acta Paediatrica Scandinavica
|March 1, 1988
Summary
Diabetic children diagnosed at a younger age experience less height loss. Early diagnosis age is a key factor in predicting growth, more so than time since diagnosis or HbA1 levels.
Area of Science:
- Pediatric Endocrinology
- Diabetology
- Growth and Development
Background:
- Childhood diabetes can impact growth and development.
- Understanding factors influencing growth in diabetic children is crucial for management.
Purpose of the Study:
- To analyze factors affecting height standard deviation score (SDS) changes in diabetic children.
- To determine the influence of age at diagnosis, time since diagnosis, and HbA1 levels on growth outcomes.
Main Methods:
- Retrospective analysis of growth data from 67 diabetic children.
- Assessment of height SDS changes over three years and from diagnosis.
- Multiple regression analysis to identify significant predictive factors.
Main Results:
- No significant correlation between factors and height SDS change over three years.
- Strong correlation between height SDS change from diagnosis, age at diagnosis, and time from diagnosis (p<0.001).
- Younger age at diagnosis correlated with less height SDS loss; age was more critical than time from diagnosis in younger children.
Conclusions:
- Early age at diagnosis is a significant protective factor against height SDS loss in diabetic children.
- Glycosylated hemoglobin (HbA1) levels did not correlate with short or long-term growth in this cohort.
- Pediatric growth in diabetic children is primarily influenced by age at diagnosis.