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Does control affect growth in diabetes mellitus?

S M Herber¹, I R Dunsmore

¹Department of Paediatrics, Sheffield Children's Hospital, University of Sheffield, UK.

Acta Paediatrica Scandinavica

|March 1, 1988

Summary

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Diabetic children diagnosed at a younger age experience less height loss. Early diagnosis age is a key factor in predicting growth, more so than time since diagnosis or HbA1 levels.

Area of Science:

Pediatric Endocrinology
Diabetology
Growth and Development

Background:

Childhood diabetes can impact growth and development.
Understanding factors influencing growth in diabetic children is crucial for management.

Purpose of the Study:

To analyze factors affecting height standard deviation score (SDS) changes in diabetic children.
To determine the influence of age at diagnosis, time since diagnosis, and HbA1 levels on growth outcomes.

Main Methods:

Retrospective analysis of growth data from 67 diabetic children.
Assessment of height SDS changes over three years and from diagnosis.
Multiple regression analysis to identify significant predictive factors.

Main Results:

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No significant correlation between factors and height SDS change over three years.
Strong correlation between height SDS change from diagnosis, age at diagnosis, and time from diagnosis (p<0.001).
Younger age at diagnosis correlated with less height SDS loss; age was more critical than time from diagnosis in younger children.

Conclusions:

Early age at diagnosis is a significant protective factor against height SDS loss in diabetic children.
Glycosylated hemoglobin (HbA1) levels did not correlate with short or long-term growth in this cohort.
Pediatric growth in diabetic children is primarily influenced by age at diagnosis.