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Silica Gel Column Chromatography: Overview01:10

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Silica gel column chromatography is a technique for separating compounds using a column packed with silica gel as the stationary phase. This method relies on differences in the polarity of compounds. Based on their polarities, compounds move between the stationary phase (silica gel) and the mobile phase (the solvent), forming discrete bands in the column.
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Updated: Nov 18, 2025

Metal-silicate Partitioning at High Pressure and Temperature: Experimental Methods and a Protocol to Suppress Highly Siderophile Element Inclusions
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Mixed Coordination Silica at Megabar Pressure.

Cong Liu1, Jiuyang Shi1, Hao Gao1

  • 1National Laboratory of Solid State Microstructures, School of Physics, and Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.

Physical Review Letters
|February 5, 2021
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Researchers discovered a new silica phase stable at extreme pressures (645-890 GPa). This mixed-coordination silica, with coordination numbers ranging from six to nine, may exist in the interiors of giant planets like Neptune.

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Area of Science:

  • Materials Science
  • Planetary Science
  • High-Pressure Physics

Background:

  • Silica (SiO2) is crucial for industrial applications and scientific research.
  • Understanding silica's behavior under extreme pressure is vital for planetary science.

Purpose of the Study:

  • To predict new crystalline phases of silica under high pressure.
  • To investigate the properties of these novel silica phases.
  • To understand the composition of giant planet interiors.

Main Methods:

  • Crystal structure searching method.
  • First-principles calculations.
  • Analysis of density, electronic band gap, and coordination number.

Main Results:

  • A new ground state crystalline phase of silica (R3[over ¯] symmetry) was predicted, stable at 645-890 GPa.
  • This phase exhibits mixed coordination numbers (six, eight, and nine) for silicon atoms, with an average of eight.
  • Stable silicon superoxides (Cmcm SiO3 and Ccce SiO6) were also identified in this pressure range.

Conclusions:

  • The new silica phase bridges existing gaps in density, band gap, and coordination number between known phases.
  • This mixed-coordination silica may be present in the cores or mantles of super-Earth exoplanets and giant planets.
  • The findings enhance the high-pressure phase diagram of silicon oxides and planetary interior models.