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Updated: Nov 18, 2025

Daily Transfers, Archiving Populations, and Measuring Fitness in the Long-Term Evolution Experiment with Escherichia coli
Published on: August 18, 2023
Fitness optimization and evolution of permanent replicator systems
Sergei Drozhzhin1, Tatiana Yakushkina2, Alexander S Bratus3,4
1Faculty of Computational Mathematics and Cybernetics, Lomonosov Moscow State University, Moscow, Russia, 119992.
Abstract:
In this paper, we discuss fitness landscape evolution of permanent replicator systems applying the hypothesis that the specific time of evolutionary adaptation of system parameters is much slower than the time of internal evolutionary dynamics. In other words, we suppose that the extremal principle of Darwinian evolution based on Fisher's fundamental theorem of natural selection is valid for the steady-states of permanent replicator systems. Various cases illustrating this concept are considered.
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