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Related Concept Videos

Burn Injuries01:22

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Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
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Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
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Updated: Nov 18, 2025

Mouse Model of Pressure Ulcers After Spinal Cord Injury
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Practice Dilemmas: Conditions That Mimic Pressure Ulcers/Injuries- To Be or Not To Be?

Melania Howell1, Salomé Loera1, Anthony Tickner2

  • 1Johns Hopkins University School of Nursing, Baltimore, Maryland.

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Pressure ulcers/injuries (PU/Is) can be misdiagnosed. This study identifies 16 conditions mimicking PU/Is, emphasizing thorough patient assessment to ensure accurate diagnosis and prevent harm.

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Area of Science:

  • Wound care and dermatology.
  • Clinical diagnostics and patient safety.

Background:

  • Pressure ulcers/injuries (PU/Is) pose significant risks, including pain, increased morbidity, and mortality.
  • While healthcare teams are aware of PU/Is, misdiagnosis remains a concern due to similar-presenting conditions.

Purpose of the Study:

  • To identify and illustrate conditions that can be mistaken for PU/Is.
  • To aid clinicians in differentiating PU/Is from other dermatological and wound presentations.

Main Methods:

  • Advanced practice wound care nurses were surveyed to identify conditions mimicking PU/Is.
  • Patient cases and photographs were collected with consent.

Main Results:

  • Sixteen distinct skin and wound presentations were identified.
  • These mimic conditions arise from diverse etiologies, including vascular diseases, infections, trauma, cancer, autoimmune disorders, coagulopathies, and organ dysfunction.

Conclusions:

  • A comprehensive patient history and physical assessment are crucial for accurate diagnosis.
  • Preventing misidentification of skin lesions as PU/Is is vital for appropriate patient management and outcomes.