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Updated: Nov 18, 2025

An Acute Retinal Model for Evaluating Blood Retinal Barrier Breach and Potential Drugs for Treatment
Published on: September 13, 2016
The choroidal rupture: current concepts and insights
Marco Lupidi1, Alessio Muzi2, Greta Castellucci2
1Department of Biomedical and Surgical Sciences, Section of Ophthalmology, University of Perugia, Perugia, Italy; Fondazione per la Macula Onlus, Di.N.O.G.Mi., University Eye Clinic, Genova, Italy; Centre de l'Odéon, Paris, France.
Abstract:
Choroidal rupture is a posterior segment affliction following a traumatic event that results in a break in the retinal pigment epithelium, Bruch membrane, and the underlying choriocapillaris. The visual prognosis may be extremely poor when involving the macular area or in cases with major comorbidities. On funduscopic examination the rupture appears as a whitish/yellowish curvilinear or crescent-shaped lesion with forked or tapered endings. Multimodal imaging including fluorescein angiography, indocyanine green angiography, optical coherence tomography, and optical coherence tomography angiography can provide a detailed assessment of the extent of damage and the onset of complications. Although there is no treatment for choroidal rupture per se, associated complications such as angle-recession glaucoma, retinal detachment, or exudative choroidal neovascularization might need therapeutic interventions. We describe the pathophysiology of choroidal rupture, the recent multimodal imaging findings, and the available treatment options for the management of complications.

