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Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
Published on: December 20, 2024
Clinical acupuncture therapy for children with allergic rhinitis: A protocol for systematic review and meta analysis
1The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Insights
This systematic review evaluates acupuncture for treating allergic rhinitis (AR) in children, offering a non-drug therapy option. Evidence suggests acupuncture is a safe and effective treatment for pediatric AR.
Area of Science:
- Pediatric Allergy and Immunology
- Complementary and Alternative Medicine
- Systematic Review and Meta-Analysis
Background:
- Allergic rhinitis (AR) is a growing concern in children, with parents seeking alternatives to drug therapies due to side effects.
- Acupuncture is increasingly recognized for its potential efficacy in managing pediatric AR.
Purpose of the Study:
- To systematically review and synthesize evidence on the safety and effectiveness of acupuncture for treating allergic rhinitis in children.
- To evaluate acupuncture as a non-pharmacological intervention for pediatric AR.
Main Methods:
- Comprehensive literature search across multiple databases (Medline, PubMed, Embase, CBM, CNKI, etc.) up to November 2020.
- Inclusion of randomized clinical trials, with data extraction and quality assessment by independent reviewers.
- Meta-analysis using RevMan 5.4.0, employing fixed or random effects models based on heterogeneity testing (P < 0.1, I² > 50%).
Main Results:
- The review will synthesize current evidence on acupuncture's efficacy in pediatric AR.
- Key outcomes include total effective rate, symptom scores (nasal, RQLQ, VAS), laboratory markers (IgE, IL6, IL10, TNF-α), recurrence rates, and adverse events.
Conclusions:
- This systematic review aims to determine if acupuncture can serve as a viable non-drug therapy for preventing or treating allergic rhinitis in children.
- Findings will inform clinical practice regarding acupuncture's role in pediatric AR management.
Background:
Allergic rhinitis (AR) in children has become a common clinical allergic disease, the incidence of which is increasing in pediatric. The side effects of the drug cause parents to worry about the health of their child. However, a large number of current clinical studies have shown that acupuncture therapy is effective in treating children with AR. Therefore, this systematic review aims to explore the safety and effectiveness of acupuncture in the treatment of AR in children.
Methods:
We will conduct a comprehensive literature search in Medline, PubMed, Cochrane Database of Systematic Reviews, Embase, Chinese Biomedical Literatures Database (CBM), China National Knowledge Infrastructure (CNKI), Wang Fang Database (WF), Chinese Scientific Journal Database (VIP) from inception to November 2020 without any language restriction. In addition, we will retrieve the unpublished studies and the references of initially included literature manually. Reviewers will identify studies, extract data, and assess the quality independently. The outcomes of interest include: total effective rate; the total nasal symptom score; Rhinitis quality of life questionnaire (RQLQ); Visual Analog Scale (VAS); Laboratory inspection indicators: the level of IgE, IL6, IL10 or TNF-α; Recurrence rate; adverse events. Randomized clinical trials will be collected, methodological quality will be evaluated using the Cochrane risk-of-bias assessment tool, and the level of evidence will be rated using the Grading of Recommendations, Assessment, Development and Evaluation approach. Meta-analysis will be performed using RevMan 5.4.0 software. The heterogeneity test will be conducted between the studies, P < .1 and I2 > 50% are the thresholds for the tests. We will utilize the fixed effects model or the random effects model according to the size of heterogeneity.
Results:
The results of this systematic review will provide a synthesis of current evidence of AR in children. We will report this result shortly.
Conclusion:
This study will explore whether or not acupuncture therapy can be used as one of the non drug therapies to prevent or treat allergic rhinitis in children.
Trial Registration Number:
INPLASY2020110053.
