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Updated: Nov 18, 2025

Clinical Application of Microscope-Assisted Minimally Invasive Anterior Lumbar Interbody Fusion
Published on: June 16, 2023
Clinical Evaluation of Microendoscopy-Assisted Oblique Lateral Interbody Fusion
Tomohide Segawa1, Hisashi Koga2,3, Masahito Oshina1
1Department of Orthopaedic Surgery, Inanami Spine and Joint Hospital, 3-17-5 Higashishinagawa, Shinagawa City, Tokyo 140-0002, Japan.
Abstract:
Background and objectives: Oblique Lateral Interbody Fusion (OLIF) is a widely performed, minimally invasive technique to achieve lumbar lateral interbody fusion. However, some complications can arise due to constraints posed by the limited surgical space and visual field. The purpose of this study was to assess the short-term postoperative clinical outcomes of microendoscopy-assisted OLIF (ME-OLIF) compared to conventional OLIF. Materials and Methods: We retrospectively investigated 75 consecutive patients who underwent OLIF or ME-OLIF. The age, sex, diagnosis, and number of fused levels were obtained from medical records. Operation time, estimated blood loss (EBL), and intraoperative complications were also collected. Operation time and EBL were only measured per level required for the lateral procedure, excluding the posterior fixation surgery. The primary outcome measure was assessed using the Japanese Orthopedic Association Back Pain Evaluation Questionnaire (JOABPEQ). The secondary outcome measure was assessed using the Oswestry Disability Index (ODI) and the European Quality of Life-5 Dimensions (EQ-5D), measured preoperatively and 1-year postoperatively. Results: This case series consisted of 14 patients in the OLIF group and 61 patients in the ME-OLIF group. There was no significant difference between the two groups in terms of the mean operative time and EBL (p = 0.90 and p = 0.50, respectively). The perioperative complication rate was 21.4% in the OLIF group and 21.3% in the ME-OLIF group (p = 0.99). In both groups, the postoperative JOABPEQ, EQ-5D, and ODI scores improved significantly (p < 0.001). Conclusions: Although there was no significant difference in clinical results between the two surgical methods, the results suggest that both are safe surgical methods and that microendoscopy-assisted OLIF could serve as a potential alternative to the conventional OLIF procedure.
Insights
Microendoscopy-assisted oblique lateral interbody fusion (ME-OLIF) offers comparable short-term clinical outcomes to conventional OLIF. Both techniques demonstrate safety and efficacy in lumbar fusion procedures, with ME-OLIF presenting a viable alternative.
Area of Science:
- Spine surgery
- Minimally invasive procedures
- Orthopedics
Background:
- Oblique Lateral Interbody Fusion (OLIF) is a common minimally invasive technique for lumbar fusion.
- Challenges in OLIF include limited surgical space and visual field, potentially leading to complications.
- Microendoscopy-assisted OLIF (ME-OLIF) aims to address these limitations.
Purpose of the Study:
- To compare the short-term postoperative clinical outcomes of ME-OLIF with conventional OLIF.
- To evaluate the safety and efficacy of both surgical approaches.
Main Methods:
- Retrospective analysis of 75 patients undergoing OLIF or ME-OLIF.
- Data collected included operative time, estimated blood loss (EBL), and intraoperative complications.
- Clinical outcomes assessed using JOABPEQ, ODI, and EQ-5D preoperatively and at 1-year postoperatively.
Main Results:
- No significant differences in operative time or EBL between OLIF and ME-OLIF groups.
- Similar perioperative complication rates (21.4% vs. 21.3%).
- Both groups showed significant improvements in JOABPEQ, EQ-5D, and ODI scores postoperatively.
Conclusions:
- ME-OLIF and conventional OLIF yield comparable short-term clinical results.
- Both methods are deemed safe for lumbar interbody fusion.
- ME-OLIF is a potential alternative to conventional OLIF.

