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Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...

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Related Experiment Video

Updated: Nov 18, 2025

Quantitative Micro-CT Analysis of Aortopathy in a Mouse Model of β-aminopropionitrile-induced Aortic Aneurysm and Dissection

Quantitative Micro-CT Analysis of Aortopathy in a Mouse Model of β-aminopropionitrile-induced Aortic Aneurysm and Dissection

Published on: July 16, 2018

Commentary: Fluoroquinolones and aortopathy-a basic (science) question?

Michael Ibrahim¹, Wilson Szeto¹

¹Division of Cardiovascular Surgery, The University of Pennsylvania, Philadelphia, Pa.

The Journal of Thoracic and Cardiovascular Surgery

|February 6, 2021

Summary

No abstract available in PubMed .

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