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Updated: Nov 18, 2025

Destabilization of the Medial Meniscus and Cartilage Scratch Murine Model of Accelerated Osteoarthritis
Published on: July 6, 2022
Failed meniscal repair increases the risk for osteoarthritis and poor knee function at an average of 9 years
Erik Rönnblad1, Björn Barenius2, Anders Stålman3
1Stockholm Sports Trauma Research Center/Karolinska Institutet, Capio Artro Clinic, Valhallavägen 91, 114 86, Stockholm, Sweden. erikronnblad@gmail.com.
Purpose:
The purpose of this study was to determine the effect of meniscal repair on OA in the knee joint and patient-related outcomes.
Methods:
Three-hundred and sixteen meniscal repairs performed between 1999 and 2011 were analysed. Patient-related outcome measures were assessed through mailed questionnaires including KOOS, Lysholm score and Tegner activity level. Patients answering the questionnaires were encouraged to perform a radiographic evaluation with Rosenberg views, assessed according to Kellgren-Lawrence (KL) classification. The primary endpoint was to determine the effect of meniscal repair on the development of radiographic OA defined as a KL grade 2 or more.
Results:
Mean follow-up time was 9.3 years (SD 3.6), 162 (51%) patients answered the questionnaires, and 86 patients completed the X-ray. The odds ratio for OA with a failed meniscus repair was 5.1 (p = 0.007) adjusted for gender and age at time of follow-up. KOOS showed a clinically important difference in the sport and recreation subscale (p = 0.041).
Conclusions:
There was an increased risk for OA in the affected compartment with a failed meniscus fixation. This supports the fact that the meniscus is an important protector of the cartilage in the knee. The meniscus injury affects the long-term health-related quality of life according to KOOS and in light of this study we recommend repair of a torn meniscus whenever possible.
Level Of Evidence:
III.
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