Related Experiment Video
Updated: Nov 18, 2025

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
Published on: June 30, 2023
Evidence of early circulation of SARS-CoV-2 in France: findings from the population-based "CONSTANCES" cohort
Fabrice Carrat1, Julie Figoni2, Joseph Henny3,4
1APHP, Département de Santé Publique, Inserm, Institut Pierre-Louis d'Epidémiologie et de Santé Publique, Sorbonne Université, 27 rue Chaligny, 75571, Paris Cedex 12, France. fabrice.carrat@iplesp.upmc.fr.
Abstract:
Using serum samples routinely collected in 9144 adults from a French general population-based cohort, we identified 353 participants with a positive anti-SARS-CoV-2 IgG test, among whom 13 were sampled between November 2019 and January 2020 and were confirmed by neutralizing antibodies testing. Investigations in 11 of these participants revealed experience of symptoms possibly related to a SARS-CoV-2 infection or situations at risk of potential SARS-CoV-2 exposure. This suggests early circulation of SARS-CoV-2 in Europe.
Related Concept Videos
Causality in Epidemiology
Bias in Epidemiological Studies
Single Nucleotide Polymorphisms-SNPs
Principles of Disease Surveillance
Confounding in Epidemiological Studies
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

