Cortical oscillations can differentiate the gradient of the simulated central visual field defect

Covert spatial attention directs the attentional spotlight to a particular part of the visual field and modulates the retinotopic organized oscillatory brain activity. This study aimed to investigate the electrophysiological characteristics of oscillatory brain activity when simulating different defect degrees of the central visual field.

The power of theta and alpha activity was extracted using time-frequency analysis in forty healthy participants enrolled in the three-stimulus oddball paradigm. Standard stimuli were black-and-white checkerboards. Target stimuli simulated different degrees of the central visual field defect by superimposing black discs with different radii (5, 10, 20, and 30 degrees of visual angle) on the center of the peripheral checkerboard stimulation, and distractor stimuli presented in the reverse form with a constant radius.

By simulating central visual field defects, the increased theta power and decreased alpha power was observed when detecting target stimuli. Besides, the magnitude of increased theta power and decreased alpha power peaked at the 10-degree defect conditions, and gradually decayed to the 5 and 30-degree defect conditions, which separately indicated two key points in the visual field through the spatial attentional modulations.

Using cortical oscillatory dynamics in the time-frequency platform, the defect category of the central visual field could be quantified by alpha and theta oscillations in power differences. These findings suggest that cortical oscillations are sensitive markers for the discrimination of gradient effects of the central visual field defects and further demonstrate the phenomenon of functional dissociation in the visual field in covert spatial attention status.