Peptides, Breathing, and Sudden Infant Death Syndrome
Nicholas J Burgraff1, Nathan A Baertsch2, Jan-Marino Ramirez3
1Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Abstract:
Shi et al. recently identified a brainstem peptidergic circuit in mice that is activated at birth and stabilizes breathing during the transition from the intra-utero environment to air breathing. This network remains important for maintaining stable breathing and respiratory homeostasis throughout development, and deficiencies in this network may be linked to sudden infant death syndrome (SIDS).
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