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Design of Solid-State Fermentation Systems for Polymer Hydrolytic Extracellular Enzyme Production by Filamentous Fungi
Published on: June 6, 2025
682
Engineering interventions in enzyme production: Lab to industrial scale.
Ayon Tarafdar1, Ranjna Sirohi2, Vivek Kumar Gaur3
1Divison of Livestock Production and Management, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly 243 122, India.
Bioresource Technology
|February 7, 2021
Summary
This review explores advancements in enzyme production, focusing on bioreactor designs and optimization strategies to enhance efficiency and sustainability for the growing industrial enzyme market. Future research directions are also highlighted.
Area of Science:
- Biotechnology
- Biochemical Engineering
Background:
- Commercial enzyme production is crucial for various industries.
- There is a growing demand for efficient, cost-effective, and sustainable enzyme production systems.
- Existing methods have limitations that necessitate new engineering interventions.
Purpose of the Study:
- To review the current global enzyme market.
- To discuss various bioreactor designs for enzyme production.
- To cover modeling and optimization strategies for enzyme production.
Main Methods:
- Review of existing literature on enzyme production technologies.
- Analysis of different bioreactor designs including membrane-based, airlift, reciprocating plate, and micro-reactors.
- Exploration of modeling and optimization techniques such as neural networks, adaptive neuro-fuzzy inference systems, and genetic algorithms.
Main Results:
- The global enzyme market is expanding, driving innovation in production.
- Novel bioreactor designs offer improved efficiency and sustainability.
- Advanced modeling and optimization techniques can significantly enhance enzyme production processes.
Conclusions:
- Engineering interventions are key to meeting the demand for industrial enzymes.
- Further research is needed in specific thrust areas to advance enzyme production technology.
- Optimized bioreactor design and process control are essential for sustainable enzyme manufacturing.

