Japanese multicenter registry evaluating the antegrade dissection reentry with cardiac computerized tomography for
Maoto Habara1, Etsuo Tsuchikane2, Kazuki Shimizu3
1Department of Cardiovascular Medicine, Toyohashi Heart Center, 21-1 Gobudori, Oyama-cho, Toyohashi, Aichi, 441-8530, Japan. habara@heart-center.or.jp.
Insights
Antegrade dissection re-entry (ADR) for chronic total occlusion (CTO) percutaneous coronary intervention (PCI) shows high success rates in Japan. Cardiac computed tomography angiography (CCTA) may improve patient and puncture site selection for ADR procedures.
Area of Science:
- Cardiovascular Interventions
- Interventional Cardiology
- Medical Imaging
Background:
- Antegrade dissection re-entry (ADR) is a key technique for chronic total occlusion (CTO) percutaneous coronary intervention (PCI).
- While ADR devices have high success rates, further improvements are sought.
- Current trends and challenges of ADR in Japan require evaluation.
Purpose of the Study:
- To evaluate current trends and issues of ADR in Japan.
- To assess the potential of cardiac computed tomography angiography (CCTA) in guiding ADR procedures.
- To analyze the correlation between CCTA findings and ADR procedural success.
Main Methods:
- 48 patients with CTO undergoing ADR were evaluated using conventional angiography and CCTA.
- Procedural and technical success rates were primary and secondary endpoints.
- Puncture sites were analyzed using CCTA, with a CT score based on plaque deposition and calcification.
Main Results:
- Overall procedure success rate was 95.8%.
- Technical success rate for ADR was 78.1% (25 out of 32 attempts), with no major complications.
- Technical success puncture sites had significantly lower CT scores compared to failure sites (0.68 vs 1.77, p < 0.0001).
Conclusions:
- CTO-PCI with the Stingray device in Japan achieves high procedural and technical success rates.
- Pre-procedural CCTA evaluation can aid in patient selection and optimal puncture site selection for ADR.
- CCTA-derived scores may predict ADR technical success.
Abstract:
Recently, antegrade dissection re-entry (ADR) with re-entry device for chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has evolved to become one of the pillar techniques of the hybrid algorithm. Although the success rate of the device is high, it could be improved. We sought to evaluate the current trends and issues associated with ADR in Japan and evaluate the potential of cardiac computed tomography angiography (CCTA) for ADR procedure. A total 48 patients with CTO suitable for ADR evaluated by baseline conventional angiography and CCTA were enrolled. Procedural success and technical success were evaluated as the primary and secondary observations. Furthermore, all puncture points were analyzed by CCTA. CT score at each punctured site depended on the location of plaque deposition (none; + 0, at isolated myocardial site; + 1, at epicardial site; + 2) and the presence of calcification (none; + 0, presence; + 1) was analyzed and calculated (score 0-3). Overall procedure success rate was 95.8%. Thirty-two cases were attempted with the ADR procedure and 25 cases of them were successful. The technical success rate was 78.1% and myocardial infarction or other major complications were not observed in any cases. CT score at 60 puncture sites in 32 cases were analyzed and the score at technical success points was significantly smaller compared to that at technical failure points (0.68 ± 1.09 vs 1.77 ± 1.09, p < 0.0001). CTO-PCI with Stingray device in Japan could achieve a high procedure success and technical success rate. Pre procedure cardiac CT evaluation might support ADR procedure for appropriate patient selection or puncture site selection.
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