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Targeted HIV screening in the emergency department
Ornella Spagnolello1, Matthew J Reed2,3
1Department of Public Health and Infectious Diseases, University of Rome Sapienza, Rome, Italy.
Internal and Emergency Medicine
|February 7, 2021
Summary
Targeted HIV screening in emergency departments (EDs) is effective and cost-efficient for diagnosing human immunodeficiency virus (HIV). This approach benefits populations often missed by traditional services, even in low-prevalence areas.
Area of Science:
- Public Health
- Infectious Diseases
- Emergency Medicine
Background:
- Rising global human immunodeficiency virus (HIV) rates necessitate innovative screening strategies.
- Emergency departments (EDs) serve diverse, often underserved populations, presenting an opportunity for HIV testing.
- Current HIV screening methods include opt-out and targeted approaches, with limited data on targeted screening effectiveness in low-prevalence settings.
Purpose of the Study:
- To review the evidence for targeted HIV screening in adult EDs across various HIV prevalence settings.
- To assess the impact, cost-effectiveness, and acceptance of targeted HIV screening in the ED.
- To explore the applicability of targeted screening in low-prevalence areas.
Main Methods:
- Literature review of studies on targeted HIV screening in adult emergency departments.
- Analysis of data from high- and low-HIV prevalence settings.
- Evaluation of screening approaches, including 'opt-out' and 'targeted' methods.
Main Results:
- Targeted HIV screening in the ED is impactful, cost-effective, and well-accepted by patients.
- Implementation challenges include the need for additional funding and staffing, particularly in resource-limited settings.
- Evidence suggests targeted screening may be suitable for both high- and low-prevalence areas.
Conclusions:
- Targeted HIV screening in EDs is a viable strategy for early diagnosis and treatment.
- The approach demonstrates effectiveness and cost-efficiency, though resource allocation is a key consideration.
- Further research and implementation in diverse settings, including low-prevalence areas, are warranted.

