[Structural-functional approach to chronic cerebral ischemia in elderly people.]
I V Khyanikyainen1, M M Burkin1, E V Molchanova2
1Petrozavodsk State University, 31 Krasnoarmeyskaya str., Petrozavodsk 185035, Russian Federation,
Abstract:
The aim of the study - experience in implementing a structural-functional approach to chronic brain ischemia (CCI) in elderly people by combining simultaneously produced measurements. Object of research - elderly patients with CCI 1 stage. As a result of the study, the methodological experience of the system study of CCI from the standpoint of the structural and functional approach in the elderly is shown. Thus, it has been demonstrated that the progression of chronic cerebral-dygemical morphological changes in the form of periventricular and subcortical leukoaareosis (according to magnetic resonance imaging) correlates with the degree of expression of cognitive dysfunction syndrome (according to the brief indicative test). Hyperhomocysteinemia are typical for patients with CCI 1 stage, what correlates with mild cognitive dysfunction. The identified biochemical, neuroimaging, neuropsychological correlates should be taken into account during medical and psychological rehabilitation of these people.
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