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Heart Retransplantation From an Hepatitis B Core Antibody (Anti-HBcore)-Positive Donor: A Case Report

Agnieszka Kuczaj1, Szymon Warwas2, Piotr Przybyłowski3

  • 1Department of Cardiac, Vascular, and Endovascular Surgery and Transplantology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Zabrze, Poland.

Transplantation Proceedings
|February 8, 2021
PubMed

Insights

Heart retransplantation using Hepatitis B core antibody-positive donors is a safe option for seronegative recipients when managed with antiviral prophylaxis. This approach can help address donor shortages in urgent heart transplantation cases.

Area of Science:

  • Cardiology
  • Transplantation Immunology
  • Infectious Diseases

Background:

  • End-stage heart failure necessitates heart transplantation, but donor shortages, especially for urgent cases, remain a significant challenge.
  • Extended-criteria donors are being considered to increase organ availability.
  • Hepatitis B virus (HBV) serological markers, such as anti-HBcore positivity, can influence donor selection.

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