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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
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The COVID-19 puzzle: a global nightmare.
Hafiza Salaha Mahrosh1, Ghulam Mustafa1
1Department of Biochemistry, Government College University, Faisalabad, 38000 Pakistan.
Environment, Development and Sustainability
|February 8, 2021
Summary
The novel coronavirus (SARS-CoV-2) causes COVID-19, a global pandemic. This review comprehensively examines SARS-CoV-2 aspects, including genomic, clinical, and environmental factors, and highlights the urgent need for effective vaccines and treatments.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- The emergence of SARS-CoV-2 in December 2019 led to a global pandemic (COVID-19).
- The virus rapidly spread worldwide, causing significant morbidity and mortality.
- Understanding SARS-CoV-2's multifaceted aspects is crucial for effective management.
Purpose of the Study:
- To provide a comprehensive overview of SARS-CoV-2.
- To discuss the genomic, epidemiological, social, clinical, and environmental characteristics of the virus.
- To review current and potential vaccine candidates against SARS-CoV-2.
Main Methods:
- Literature review and synthesis of existing data on SARS-CoV-2.
- Analysis of genomic, clinical, and epidemiological information.
- Evaluation of current vaccine development strategies and candidates.
Main Results:
- SARS-CoV-2 utilizes the human ACE2 receptor for cell entry, similar to SARS-CoV.
- Clinical symptoms are non-specific, including fever and respiratory issues, with characteristic X-ray findings.
- No fully effective drug or vaccine is currently validated, emphasizing the need for further development.
Conclusions:
- There is an urgent need for effective vaccines and treatments against SARS-CoV-2.
- Several vaccine candidates, including mRNA-1273 and ChAdOx1, show promise.
- Continued research into pathogenesis and vaccine development is essential to combat the COVID-19 pandemic.
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