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Updated: Nov 18, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Exploding Head Syndrome Accompanied by Repeating Panic Attacks: A Case Report.

Yoshiyuki Kaneko1, Akiomi Kawae1, Kaori Saitoh1,2

  • 1Department of Psychiatry, Nihon University School of Medicine, Tokyo, Japan.

Frontiers in Psychiatry
|February 8, 2021
PubMed
Summary
This summary is machine-generated.

Exploding head syndrome (EHS) can trigger panic attacks. This case study shows treatment with clonazepam and reassurance effectively resolved EHS symptoms and associated anxiety.

Keywords:
case reportclonazepamexploding head syndromepanic attackparasomniasleep disorder

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Area of Science:

  • Neurology
  • Sleep Medicine
  • Psychiatry

Background:

  • Exploding head syndrome (EHS) is a rare parasomnia characterized by a loud, sudden noise experienced by the patient before sleep.
  • The exact etiology of EHS remains unclear, but it is generally considered benign.

Observation:

  • A 62-year-old woman presented with recurrent episodes of EHS, occurring multiple times nightly.
  • These episodes led to a significant fear of sleep and the development of nocturnal panic attacks.

Findings:

  • The patient was diagnosed with EHS and treated with clonazepam and supportive counseling.
  • Treatment resulted in a gradual reduction in the intensity of EHS episodes and complete resolution of sleep-related fear and panic attacks.

Implications:

  • This case highlights the potential for EHS to complicate psychiatric conditions, specifically panic disorder.
  • Further research into the psychiatric comorbidities and optimal treatment strategies for EHS is warranted.